Study on Nutritional and Health Management Strategies for Benign Tumors in Companion Animals: A Focus on Lipoma
DOI:
https://doi.org/10.70088/q3g7sx44Keywords:
canine lipoma, benign tumor, nutritional regulation, lipid metabolism, weight managementAbstract
Canine lipoma is the most common benign soft-tissue tumor encountered in veterinary clinical practice, representing approximately 12% of all canine cutaneous tumors. With increasing pet longevity and evolving feeding practices, its detection rate continues to show a steady year-on-year rise. Traditional surgical resection carries a relatively high recurrence rate and significant anesthesia-related risks for geriatric dogs, driving growing interest in alternative nutritional regulation strategies. This review systematically summarizes the epidemiological characteristics of canine lipoma and analyzes the impact of specific dietary components—including medium-chain triglycerides, epigallocatechin gallate, and curcumin—on anti-inflammatory responses, lipid metabolism regulation, and lipogenesis inhibition. Furthermore, a comprehensive nutritional intervention program centered on weight management is proposed. The study also examines the synergistic regulatory effects of medicinal mushroom-based formulations on immune modulation, anti-inflammatory activity, and metabolic reprogramming, ultimately developing a functional supplementation strategy. Dogs serve as the primary research model due to the high incidence of lipomas, abundant epidemiological data, and significant clinical challenges, such as nerve compression and impaired mobility. The strong demand for non-surgical, conservative treatments among pet owners further justifies this focus. Because the pathogenesis of canine lipoma shares similarities with benign lipomas in other mammals, these proposed nutritional intervention strategies may improve clinical management in dogs while providing valuable translational insights for non-surgical interventions in other animals and potentially humans.References
M. Lappalainen, J. Gomez Fernandez, J. Béguin, Q. Fournier, A. Hayes, Y. Bing, ... and I. Desmas-Bazelle, "Presentation, treatment, and outcome of lipomas of the pelvic canal in dogs," Veterinary Oncology, vol. 2, no. 1, p. 28, 2025.
G. C. M. Emerick, B. L. Becalli, J. V. R. Junior, H. V. Sheid, and C. Marcolongo‐Pereira, "Chondro‐Osteoblastic lipoma in a dog," Veterinary Record Case Reports, vol. 13, no. 4, p. e70224, 2025.
M. P. L. da Silva Mattos, L. C. Stolf, and R. K. Carneiro, "Ultrasonographic and computed tomographic findings of an intra-abdominal lipoma in a dog," Veterinary Research Communications, vol. 50, no. 2, p. 119, 2026.
I. Quinonero Reinaldos, M. Erskine, and R. Coe, "Recurrent lipoma in the common calcaneal tendon sheath in a dog," Veterinary Record Case Reports, vol. 13, no. 4, p. e70189, 2025.
H. S. Seo, H. Y. Kim, J. M. Kim, J. S. Cho, S. Lee, and D. Park, "Modified Stabilization Technique Following Resection of a Massive Cervical Infiltrative Lipoma with Spinal Compression in a Dog," Animals, vol. 16, no. 5, p. 747, 2026.
S. Rai and V. P. Chandrapuria, "Surgical management of lipoma in a dog," Indian Journal of Canine Practice Volume, vol. 7, no. 1, 2015.
H. H. Huang, W. Y. Chen, and S. C. Chang, "Obese and senior factors increase the incidence of lipoma in dogs with non-malignant skin mass," *Taiwan Veterinary Journal*, vol. 44, no. 4, pp. 197-204, 2018.
B. Lamagna, A. Greco, A. Guardascione, L. Navas, M. Ragozzino, O. Paciello, ... and L. Meomartino, "Canine lipomas treated with steroid injections: clinical findings," PloS one, vol. 7, no. 11, p. e50234, 2012.
M. C. McEntee and D. E. Thrall, "Computed tomographic imaging of infiltrative lipoma in 22 dogs," Veterinary Radiology & Ultrasound, vol. 42, no. 3, pp. 221-225, 2001.
B. Pakhrin, M. S. Kang, I. H. Bae, M. S. Park, H. Jee, M. H. You, ... and D. Y. Kim, "Retrospective study of canine cutaneous tumors in Korea," Journal of Veterinary Science, vol. 8, no. 3, p. 229, 2007.
B. A. Kramek, C. J. Spackman, and D. W. Hayden, "Infiltrative lipoma in three dogs," Journal of the American Veterinary Medical Association, vol. 186, no. 1, pp. 81-82, 1985.
R. R. Huppes, N. Dal Pietro, M. C. Wittmaack, G. Sembenelli, C. M. Bueno, J. M. Pazzini, ... and J. L. C. Castro, "Intermuscular lipoma in dogs," Acta Scientiae Veterinariae, vol. 44, pp. 1-7, 2016.
G. A. Ramirez, J. Altimira, B. Garcia, and M. Vilafranca, "Chondro-osteoblastic metaplasia in canine benign cutaneous lipomas," Journal of Comparative Pathology, vol. 142, no. 1, pp. 89-93, 2010.
D. G. O’Neill, C. H. Corah, D. B. Church, D. C. Brodbelt, and L. Rutherford, "Lipoma in dogs under primary veterinary care in the UK: prevalence and breed associations," Canine Genetics and Epidemiology, vol. 5, no. 1, p. 9, 2018.
A. E. McChesney, L. C. Stephens, J. Lebel, S. Snyder, and H. R. Ferguson, "Infiltrative lipoma in dogs," Veterinary Pathology, vol. 17, no. 3, pp. 316-322, 1980.
M. K. Kok, J. K. Chambers, M. Tsuboi, R. Nishimura, H. Tsujimoto, K. Uchida, and H. Nakayama, "Retrospective study of canine cutaneous tumors in Japan, 2008–2017," Journal of veterinary medical science, vol. 81, no. 8, pp. 1133-1143, 2019.
G. Avallone, V. Pellegrino, L. V. Muscatello, G. Sarli, and P. Roccabianca, "Spindle cell lipoma in dogs," 2017.
A. Volta, M. Bonazzi, G. Gnudi, M. Gazzola, and G. Bertoni, "Ultrasonographic features of canine lipomas," Veterinary Radiology & Ultrasound, vol. 47, no. 6, pp. 589-591, 2006.
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