Genomic Surveillance of Dengue Virus Outbreaks in Southeast Asia: Implications for Regional Vaccine Efficacy
DOI:
https://doi.org/10.70088/m6ak5y09Keywords:
Dengue virus, Genomic surveillance, Vaccine efficacy, Southeast Asia, Virus evolutionAbstract
Rivet on implication for vaccine efficacy, this research article inquire the surveillance of dengue virus outbreaks in Southeast Asia. Utilizing advance sequence engineering and bioinformatics tools, the study discover sport in circle dengue virus strains and evaluates their encroachment on vaccine performance. Accentuate the need for adaptive vaccine strategies, the finding foreground the nature of dengue virus evolution in the neighborhood. This study contributes to read the interplay between diverseness and vaccine efficacy. Provide perceptivity for health interventions target at extenuate dengue outbreaks.References
K. S. Lee, S. Lo, S. S. Y. Tan, R. Chua, L. K. Tan, H. Xu, and L. C. Ng, "Dengue virus surveillance in Singapore reveals high viral diversity through multiple introductions and in situ evolution," Infect., Genet. Evol., vol. 12, no. 1, pp. 77-85, 2012.
J. A. Usme-Ciro, J. A. Méndez, K. D. Laiton, and A. Páez, "The relevance of dengue virus genotypes surveillance at country level before vaccine approval," Hum. Vaccines Immunother., vol. 10, no. 9, pp. 2674-2678, 2014.
S. Fahri et al., "Molecular surveillance of dengue in Semarang, Indonesia revealed the circulation of an old genotype of dengue virus serotype-1," PLoS Negl. Trop. Dis., vol. 7, no. 8, p. e2354, 2013.
T. Tsheten, D. J. Gray, A. C. Clements, and K. Wangdi, "Epidemiology and challenges of dengue surveillance in the WHO South-East Asia Region," Trans. R. Soc. Trop. Med. Hyg., vol. 115, no. 6, pp. 583-599, 2021.
L. Li et al., "A unified global genotyping framework of dengue virus serotype-1 for a stratified coordinated surveillance strategy of dengue epidemics," Infect. Dis. Poverty, vol. 11, no. 1, p. 107, 2022.
C. J. Stica, R. A. Barrero, R. Z. Murray, G. J. Devine, M. J. Phillips, and F. D. Frentiu, "Global evolutionary history and dynamics of dengue viruses inferred from whole genome sequences," Viruses, vol. 14, no. 4, p. 703, 2022.
K. Edenborough et al., "Dengue virus genomic surveillance in the applying Wolbachia to eliminate dengue trial reveals genotypic efficacy and disruption of focal transmission," Sci. Rep., vol. 14, no. 1, p. 28004, 2024.
K. S. Lee et al., "Dengue virus surveillance for early warning, Singapore," Emerging Infect. Dis., vol. 16, no. 5, p. 847, 2010.
X. Guo et al., "GISDD: A comprehensive global integrated sequence and genotyping database platform for dengue virus, facilitating a stratified coordinated surveillance strategy," iMetaOmics, vol. 2, no. 4, p. e70048, 2025.
V. Hill et al., "A new lineage nomenclature to aid genomic surveillance of dengue virus," PLoS Biol., vol. 22, no. 9, p. e3002834, 2024.
M. J. Schreiber et al., "Genomic epidemiology of a dengue virus epidemic in urban Singapore," J. Virol., vol. 83, no. 9, pp. 4163-4173, 2009.
F. M. Heralde III, G. B. Obra, and M. P. B. Apelado, "Genomic surveillance and intervention on dengue virus in an urban setting in the Philippines," in Dengue fever in a one health perspective-latest research and recent advances. IntechOpen, 2023.
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Copyright (c) 2025 Lei Zhao (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
