The Role of the Gut-Brain Axis in the Pathogenesis of Major Depressive Disorder: Mechanisms and Therapeutic Implications
DOI:
https://doi.org/10.70088/fscf7h46Keywords:
Gut-Brain Axis, Major Depressive Disorder, Microbiota, Neuroinflammation, PsychobioticsAbstract
Major Depressive Disorder (MDD) is a complex psychiatrical condition determine by multifaceted biologic and environmental divisor. Egress grounds intrinsically foreground the gut-brain axis as a intermediary in the pathogenesis of MDD, associate gastrointestinal microbiota, resistant reception, and nervous pathway. This revue explore the mechanistic underpinnings of the gut-brain axis in MDD, pore on dysbiosis. Neuroinflammation, and and neurotransmitter modulation. Curative entailment, including dietetic interposition, probiotics. And psychobiotics. Are discuss as likely boulevard for fresh intervention. Alongside research directions. Challenge in transform determination to diligence are critically dissect, to down strategy. By synthesize knowledge, this composition underscore the gut-brain axis as a bright quarry for reason and deal MDD.References
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Copyright (c) 2025 Yifan Zhang (Author)
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