Research Progress on the Basis and Clinical Applications of Peiyuan Anti-Cancer Decoction in the Treatment of Oncological Diseases

Authors

  • Yuanyue Zhang Shaanxi University of Chinese Medicine, Xianyang, China Author
  • Hailong Si The First Clinical Medical College of Shaanxi University of Chinese Medicine, Xianyang, China Author

DOI:

https://doi.org/10.70088/2sr4h907

Keywords:

peiyuan anti-cancer decoction, integrative oncology, tumor microenvironment, chemotherapy, traditional chinese medicine

Abstract

Malignant tumors represent a major global public health challenge, characterized by persistently high incidence and mortality rates that demand innovative therapeutic strategies. Peiyuan Anti-Cancer Decoction, a representative traditional Chinese medicine (TCM) formula in integrative oncology, has attracted considerable attention in both basic experimental research and clinical practice in recent years. Grounded in the TCM principle of strengthening the body's vital qi while eliminating pathogenic factors, this formula exerts anti-tumor effects through multi-target, multi-pathway synergistic mechanisms. These include modulation of immune function, regulation of tumor cell signaling pathways, enhancement of radiotherapy and chemotherapy efficacy with concurrent toxicity reduction, and improvement of patients' clinical symptoms and overall quality of life. Accumulating clinical evidence indicates that Peiyuan Anti-Cancer Decoction can augment the therapeutic effectiveness of conventional radiotherapy and chemotherapy, alleviate treatment-related adverse effects, and, to a certain extent, prolong survival in the comprehensive management of malignant tumors such as lung cancer and primary liver cancer. Its core therapeutic value lies in integrating the strengths of both medical systems by combining the Western medicine paradigm of direct tumor targeting with the TCM strategy of regulating the internal physiological environment, thereby establishing an integrated treatment model that harmonizes offensive and defensive therapeutic approaches. This paradigm aligns with the contemporary shift in oncology from single-target confrontation toward holistic balance. This article systematically reviews the mechanisms of action, clinical efficacy, and current research status of Peiyuan Anti-Cancer Decoction, and discusses future development directions, aiming to provide a valuable reference for optimizing integrative oncology treatment strategies.

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Published

08 August 2026

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How to Cite

Zhang, Y. and Si, H. (2026) “Research Progress on the Basis and Clinical Applications of Peiyuan Anti-Cancer Decoction in the Treatment of Oncological Diseases”, Medicine Insights, 3(3), pp. 89–98. doi:10.70088/2sr4h907.