Prognostic Role of the Triglyceride Glucose Index on All-Cause, Cardiovascular, and Cause-Specific Mortality in Adult Gastric Cancer Patients

Authors

  • Qinglong Jian Department of Emergency and Disaster Medicine Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Author
  • Zhifeng Mo Department of Emergency and Disaster Medicine Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Author
  • Huilong Guo Department of Emergency and Disaster Medicine Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Author
  • Rongxiang Sun Department of Emergency and Disaster Medicine Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Author

DOI:

https://doi.org/10.70088/btv7ge91

Keywords:

gastric cancer, triglyceride glucose index (TyG), mortality, cardiovascular diseases, prognostic analysis

Abstract

Objective: To evaluate the link between the triglyceride-glucose index (TyG) and the risk of death in adults diagnosed with gastric cancer, utilizing data from the National Health and Nutrition Examination Survey (NHANES). Method: To understand the relationship between TyG levels and mortality outcomes in gastric cancer patients, we applied Cox proportional hazards models, Kaplan-Meier curves, and restricted cubic spline analyses. Result: Our findings indicated that participants in the highest TyG quartile showed a significant rise in mortality from all causes, heart-related deaths, and gastric cancer compared to those in the lowest quartile. There was a linear correlation between TyG and both all-cause and cardiovascular mortality, underscoring TyG's potential as a prognostic marker. Conclusion: The research highlights a strong link between TyG and mortality rates in adults with gastric cancer, indicating that keeping track of TyG could be vital for clinical management and risk assessment in this group. Future investigations need to delve deeper into the biological mechanisms behind these associations.

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Published

12 September 2026

Issue

Vol. 3 No. 4 (2026)

Section

Article

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Copyright (c) 2026 Qinglong Jian, Zhifeng Mo, Huilong Guo, Rongxiang Sun (Author)

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Jian, Q. (2026) “Prognostic Role of the Triglyceride Glucose Index on All-Cause, Cardiovascular, and Cause-Specific Mortality in Adult Gastric Cancer Patients”, Medicine Insights, 3(4), pp. 41–52. doi:10.70088/btv7ge91.