Impact of Emergency Department Triage Process Optimization on the Prevention and Control of Cross-Infection: A Systematic Review

Authors

  • Fang Li The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Author
  • Yu Qian The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Author

DOI:

https://doi.org/10.70088/d0bmkj17

Keywords:

emergency department, triage, process optimization, cross-infection, infection prevention and control, systematic review

Abstract

Objective To systematically evaluate the influence of emergency department (ED) triage process optimization on the prevention and control of cross-infection, to identify the intervention components supported by current evidence, and to grade the certainty of that evidence. Methods Following the PRISMA 2020 statement, eight Chinese and English databases (CNKI, Wanfang, CBM, PubMed, Embase, Web of Science, Cochrane Library and WHO IRIS) were searched from January 2020 to December 2025 for studies linking ED triage process optimization-pre-checkpoint screening, rapid pathogen detection, intelligent decision support, zoning and isolation restructuring, and patient flow management-with cross-infection related outcomes; foundational earlier works were added through citation searching. Methodological quality was appraised with AMSTAR-2, Joanna Briggs Institute (JBI) tools and AGREE II, and outcome-level certainty was rated with the GRADE approach. Results of 2 417 records retrieved, 22 studies were included, 19 of which were published within the recent five years. Rapid molecular screening at the ED entrance shortened the median time to pathogen result from 22.2 hours to 3.1 hours (P<0.001), reduced antibiotic administration at admission from 80.3% to 66.1% (P<0.001) and, combined with empiric contact precautions, was associated with a fall in carbapenem-resistant Enterobacterales acquisition from 4.6% to 1.0% and in antimicrobial consumption from 804 to 394 defined daily doses per 1 000 patients. Machine-learning triage models achieved superior discrimination to conventional scales (AUROC 0.917 vs 0.882), and big-data driven whole-process triage management raised triage concordance to 98.49% while shortening waiting time. Thirteen studies (59.1%) were rated high quality; outcome-level certainty was moderate for detection speed and antimicrobial stewardship and low to very low for multidrug-resistant organism acquisition and flow outcomes. Conclusion Triage process optimization functions as a transmission-interruption instrument at the hospital gateway rather than as a purely administrative procedure; its infection-control benefit depends on bundling rapid diagnostics, accurate stratification, pre-emptive isolation, crowding relief and continuous data feedback within adequately resourced infection prevention and control programmes. This review further finds that the certainty of the evidence is inversely related to its clinical importance, so its most consequential claims remain provisional and warrant standardised, multicentre prospective testing.

References

World Health Organization, Global Report on Infection Prevention and Control: Executive Summary, Geneva, Switzerland: World Health Organization, 2022. ISBN 978-92-4-004974-1.

R. N. Hoot and D. Aronsky, "Systematic review of emergency department crowding: causes, effects, and solutions," Annals of Emergency Medicine, vol. 52, no. 2, pp. 126–136, 2008, doi: 10.1016/j.annemergmed.2008.03.014.

D. L. Schriger, "Learning from the decrease in US emergency department visits in response to the coronavirus disease 2019 pandemic," JAMA Internal Medicine, vol. 180, no. 10, pp. 1334–1335, 2020, doi: 10.1001/jamainternmed.2020.3265.

A. S. Al-Shareef, A. Al Jabarti, K. A. Babkair, et al., "Strategies to improve patient flow in the emergency department during the COVID-19 pandemic: a narrative review of our experience," Emergency Medicine International, vol. 2022, p. 2715647, 2022, doi: 10.1155/2022/2715647.

M. Knowles, G. Aref-Adib, S. Moslehi, et al., "Containing COVID: the establishment and management of a COVID-19 ward in an adult psychiatric hospital," BJPsych Open, vol. 6, no. 6, p. e140, 2020, doi: 10.1192/bjo.2020.126.

M. C. Salomão, M. P. Freire, C. S. Lázari, et al., "Transmission of carbapenem-resistant Enterobacterales in an overcrowded emergency department: controlling the spread to the hospital," Clinical Infectious Diseases, vol. 77, no. S1, pp. S46–S52, 2023, doi: 10.1093/cid/ciad263.

M. Eveillard, C. Leroy, F. Teissiere, et al., "Impact of selective screening in the emergency department on meticillin-resistant Staphylococcus aureus control programmes," Journal of Hospital Infection, vol. 63, no. 4, pp. 380–384, 2006, doi: 10.1016/j.jhin.2006.02.020.

C. Knieß, J. Kelly, P. Dominici, et al., "366 Does the emergency department recognize and isolate obvious Clostridium difficile diarrhea?," in Annals of Emergency Medicine, vol. 66, no. 4S, p. S132, 2015, doi: 10.1016/j.annemergmed.2015.07.402.

A. Kumar, B. Abbenbroek, A. Delaney, et al., "Sepsis triggers and tools to support early identification in healthcare settings: an integrative review," Australian Critical Care, vol. 36, no. 6, pp. 1117–1128, 2023, doi: 10.1016/j.aucc.2023.01.001.

L. Evans, A. Rhodes, W. Alhazzani, et al., "Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021," Intensive Care Medicine, vol. 47, no. 11, pp. 1181–1247, 2021, doi: 10.1007/s00134-021-06506-y.

G. Waligora, R. Sherwin, and Z. Soucy, "Can application of artificial intelligence improve emergency department triage performance?," The Journal of Emergency Medicine, vol. 78, pp. 351–370, 2025, doi: 10.1016/j.jemermed.2025.04.001.

S. Tyler, M. Olis, N. Aust, et al., "Use of artificial intelligence in triage in hospital emergency departments: a scoping review," Cureus, vol. 16, no. 5, p. e59906, 2024, doi: 10.7759/cureus.59906.

S. Ouellet, M. C. Gallani, G. Fontaine, et al., "Strategies to improve the quality of nurse triage in emergency departments: a systematic review," International Emergency Nursing, vol. 81, p. 101639, 2025, doi: 10.1016/j.ienj.2025.101639.

Y. Wang, Y. Liu, C. Chen, et al., "Application of HIT Technology and Big Data Analysis in Intelligent Emergency Pre-screening and Triage," Chinese Journal of Emergency Medicine, vol. 32, no. 6, pp. 846–849, 2023, doi: 10.3760/cma.j.issn.1671-0282.2023.06.027.

C. Li, T. T. Li, R. F. Li, et al., "Current Status and Improvement Discussion of Emergency Pre-screening and Triage Based on RETTSChina," Chinese Journal of Emergency Medicine, vol. 33, no. 8, pp. 1177–1180, 2024, doi: 10.3760/cma.j.issn.1671-0282.2024.08.017.

M. Yang, A. Wu, A. Wu, et al., "Practical Experience of the Whole Process Management of Emergency Pre-screening Based on Big Data Feedback," China Nursing Management, vol. 24, no. 8, pp. 1204–1208, 2024, doi: 10.3969/j.issn.1672-1756.2024.08.016.

C. Tang, S. Wang, M. Guo, et al., "Design and Application of the Information-based Emergency Department Triage and Registration Process Based on Process Reengineering Theory," China Nursing Management, vol. 24, no. 8, pp. 1198–1204, 2024, doi: 10.3969/j.issn.1672-1756.2024.08.015.

M. J. Page, J. E. McKenzie, P. M. Bossuyt, et al., "The PRISMA 2020 statement: an updated guideline for reporting systematic reviews," Journal of Clinical Epidemiology, vol. 134, pp. 178–189, 2021, doi: 10.1016/j.jclinepi.2021.03.001.

G. Cambien, J. Guihenneuc, L. Dero, et al., "Impact of rapid screening of respiratory viral infections on patient management in a health care facility," The Journal of Hospital Infection, vol. 167, pp. 192–198, 2025, doi: 10.1016/j.jhin.2025.10.018.

P. Sitthiprawiat, B. Wittayachamnankul, W. Sirikul, et al., "Development and internal validation of an AI-based emergency triage model for predicting critical outcomes in emergency department," Scientific Reports, vol. 15, no. 1, p. 31212, 2025, doi: 10.1038/s41598-025-17180-1.

S. S. Mohsin, O. H. Salman, A. A. Jasim, et al., "A real-time web-based telemedicine framework based on AI and IoMT for emergency triage and initial diagnostics: the TeleMedQuick solution," International Journal of Medical Informatics, vol. 204, p. 106074, 2025, doi: 10.1016/j.ijmedinf.2025.106074.

E. E. Austin, B. Blakely, C. Tufanaru, et al., "Strategies to measure and improve emergency department performance: a scoping review," Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, vol. 28, no. 1, p. 55, 2020, doi: 10.1186/s13049-020-00749-2.

Downloads

Published

01 October 2026

Issue

Section

Article

How to Cite

Li, F. and Qian, Y. (2026) “Impact of Emergency Department Triage Process Optimization on the Prevention and Control of Cross-Infection: A Systematic Review”, Medicine Insights, 3(5), pp. 1–17. doi:10.70088/d0bmkj17.